Case Studies

PROMIS® Emotional Distress and Sleep Disturbance Short Forms used in DSM-5 Field Trials

PROMIS adult, pediatric, and parent-proxy Depression, Anxiety, Anger, and Sleep Disturbance banks were selected as Level 2 cross-cutting symptom measures for inclusion in the American Psychiatric Association’s Diagnostic and Statistical Manual of Mental Disorders – Fifth edition (DSM-5).

The selection of these measures highlights the utility of self- and proxy-report measurement tools in a clinical context. Measures can be used to identify areas of mental health requiring clinical investigation and likely intervention, as well as systematically tracking changes in symptom levels over time.

The inclusion of these measures in a clinical context further supports the applicability of PROMIS within both the clinical and research communities, facilitating a stronger relationship between clinical practice and health outcomes research.

Patient-Centered Outcomes Research Institute (PCORI) acknowledges the importance of the PROMIS initiative with extensive funding opportunities

Since its first funding announcement in 2012, PCORI has awarded nearly $27 million to studies using PROMIS measures. In addition to a PROMIS-specific funding announcement in 2014 totaling $5 million in support, PCORI continues to recognize the importance of PROMIS by soliciting input on the future involvement of PROMIS’ methodology and measures within its research portfolio.

Click here for a listing of PCORI awards as of March 2016 using PROMIS methods and measures.

Results of the inaugural pilot studies featuring PROMIS measures are now available at pcori.org.

Pediatric Imaging, Neurocognition, and Genetics (PING) study creates large data repository, includes NIH Toolbox® Cognition Battery (NTCB)

The NIH Toolbox Cognition Battery was administered to a representative sample of 1,493 children ranging in age from 3 to 20 years. In addition to the NTCB data, standardized high-resolution structural and functional MRI brain images, comprehensive genomic profiles, neuropsychiatric medical histories, and social-emotional health and substance use assessment data collected using the PhenX Toolkit are also available for download. The dataset is available via the PING Data Resource portal along with the study’s methodology and information about the consortium.

A separate data exploration portal is also available to support collaborative analysis and visualization of the dataset.