Preference-based Scores

Preference-based scores provide an overall summary of health-related quality of life on a common metric.

Preference-based scores summarize multiple domains on a metric ranging from 0 (as bad as dead) to 1 (perfect or ideal health). Scores can be used in comparisons across groups and for cost-utility analyses. 

PROMIS-Preference (PROPr) Score

The PROMIS-Preference (PROPr) score is a generic, societal, preference-based summary score. It is based on PROMIS scores for Cognition (Cognitive Function or Cognitive Function Abilities), Depression, Fatigue, Pain Interference, Physical Function, Sleep Disturbance, and Ability to Participate in Social Roles and Activities. Learn more about PROPr>>

PROPr Requires 7 PROMIS Domains

An analyst can calculate a PROPr score with scores from 7 PROMIS domains. There are three options for obtaining the necessary data:

1. Administer computer adaptive tests (CATs) for:

  • PROMIS Cognitive Function v2.0 or Cognitive Function – Abilities v2.0
  • PROMIS Depression v1.0
  • PROMIS Fatigue v1.0
  • PROMIS Pain Interference v1.0 or v1.1
  • PROMIS Physical Function v1.0, v1.1, v1.2 or v2.0
  • PROMIS Sleep Disturbance v1.0
  • PROMIS Ability to Participate in Social Roles and Activities v2.0

2. Administer the PROMIS-29 Profile v2.0 and two items from Cognitive Function – Abilities v2.0

  • PC6r: In the past 7 days, I have been able to concentrate. 1=Not at all, 2=A little bit, 3=Somewhat, 4=Quite a bit, 5=Very much
  • PC27r: In the past 7 days, I have been able to remember to do things, like take medicine or buy something I needed. 1=Not at all, 2=A little bit, 3=Somewhat, 4=Quite a bit, 5=Very much

3. Administer the PROMIS-29 Profile v2.0 and a PROMIS Cognitive Function – Abilities or PROMIS Cognitive Function short form (e.g., 4a).

The PROMIS-Preference score was constructed using the Cognitive Function - Abilities Subset v2.0 Item Bank. To get a cognition estimate to calculate a PROPr score, you can either use Cognitive Function - Abilities Subset v2.0 or Cognitive Function v2.0. Since both measures are co-calibrated using IRT, their scores are comparable.

Access PROPr Scoring Software Code

PROPr is calculated from the scores for the 7 PROMIS domains. PROMIS domain scores can be calculated using the HealthMeasures Scoring Service. See Calculate Scores for more information>>

Once you have theta scores, apply SAS or R code to calculate a PROPr score. The code is named “MAUT” (Multi-Attribute Utility Theory) and available at https://github.com/janelhanmer/PROPr

Other PROMIS Preference-based Summary Scores

EQ-5D preference-based health index scores can be estimated from the PROMIS Global Health scale. To learn more, see Thompson et al (2017). Scoring instructions are included in the PROMIS Global Scoring Manual.

Health Utilities Index Mark 3 (HUI-3) preference scores can be estimated from the PROMIS-29 v2.0 Profile (preferred) or PROMIS Global Health scale. For more information and scoring equations, see Hays et al (2016).