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  PROMIS is a measurement system within HealthMeasures. It provides precise patient-reported outcome (PRO) measures for physical, mental, and social health.
  
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- Neuro-QoL™ & NIH Toolbox®
  
  Neuro-QoL and NIH Toolbox are measurement systems within HealthMeasures. Neuro-QoL provides patient-reported outcome (PRO) measures of physical, mental, and social health experienced by adults and children living with neurological conditions. NIH Toolbox provides PRO measures of emotion and performance-based tests of cognition, motor function, and sensation.
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Home » Select Measures » Compare Measurement Systems » Comparison Table

Comparison Table

Key Features of Measurement Systems

PROMIS®	Neuro-QoL™	ASCQ-Me®	NIH Toolbox®
• People with health conditions • General population	• People with neurological conditions	• People with sickle cell disease	• People with health conditions • General population

	PROMIS	Neuro-QoL	ASCQ-Me	NIH Toolbox
Self-report measures	X	X	X	Emotion and some Sensation measures
Proxy measures for pediatrics	X	X		Emotion measures
Proxy measures for adults		X
Performance tests of cognitive, motor, sensory function				X

	PROMIS	Neuro-QoL	ASCQ-Me	NIH Toolbox
Adults	X	X	X	X
Children	• Ages 8-17 self-report • Ages 1-17 parent proxy report	• Ages 8-17 self-report • Ages 8-17 proxy report		• Ages 8-17 self-report • Ages 3-12 parent report

	PROMIS	Neuro-QoL	ASCQ-Me	NIH Toolbox
Short Forms	X	X	X	X
Computer Adaptive Tests	X	X	X	X
Profiles	X

	PROMIS	Neuro-QoL	ASCQ-Me	NIH Toolbox
English	X	X	X	X
Spanish	X	X	X	X
Other	X	X	X	X

	PROMIS	Neuro-QoL	ASCQ-Me	NIH Toolbox
Paper and pencil	X	X	X	Emotion and some Sensation measures
Computer administration	X	X	X	X

	PROMIS	Neuro-QoL	ASCQ-Me	NIH Toolbox
Paper	X	X	X	Emotion and some Sensation measures
Assessment Center API (used by REDCap and other ePRO platforms)	X	X	X	Emotion and some Sensation measures
NIH Toolbox iPad App	Selected measures			X
Epic 2017 and later	Selected measures

	PROMIS	Neuro-QoL	ASCQ-Me	NIH Toolbox
Development funded by the NIH	X	X	X	X
Person-centered	X	X	X	X
Psychometrically sound	X	X	X	X
Standardized scoring	X	X	X	X
Brief completion time	X	X	X	X

	PROMIS	Neuro-QoL	ASCQ-Me	NIH Toolbox
Administrator training required				Cognition, Sensation, and Motor measures only
Approval required to access measures				Cognition only
Approval required for integration into digital administration platforms	X	X	X	X

Last updated: September 28, 2026